Diagnosis of MDS or MDS/MPN must begin with morphology (analysis of the form and structure of patient blood or bone marrow cells). When used alone, today’s advanced techniques to study genes and chromosomes don’t give enough information to find out what type of MDS or MDS/MPN a patient has.
Read more about Drivers or Passengers? Genetics of MDS and MDS/MPN
Conventional cytogenetics is a method to analyze chromosomes. Researchers and clinicians use conventional cytogenetics to diagnose blood disorders, predict outcomes in patients with these disorders, and develop new treatments that target genetic changes associated with a disease.
Read more about There is Always Room for Improvement: Changing Role of Chromosome Analysis in MDS and MDS/MPN.
Different types of MDS/MPN have similar symptoms but profoundly different outcomes. The type and intensity of treatment must be tailored to each patient’s type of MDS/MPN. Therefore, it is important to diagnose these diseases accurately.
Read more about Bridging the Overlap Gap: Understanding the Natural History of Myelodysplastic/ Myeloproliferative Neoplasm (MDS/MPN)